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Goodbye. no fanfare, no sifttalk post. (Blog Entry by smibbo)
Boarding a train that does not need to stop to pick you up
Study Proves That we Want to be Fat
Neuron, Volume 58, Issue 2, 24 April 2008, Page 295
Ivan E. de Araujo, Albino J. Oliveira-Maia, Tatyana D. Sotnikova, Raul R. Gainetdinov, Marc G. Caron, Miguel A.L. Nicolelis and Sidney A. Simon
Summary
Food palatability and hedonic value play central roles in nutrient intake. However, postingestive effects can influence food preferences independently of palatability, although the neurobiological bases of such mechanisms remain poorly understood. Of central interest is whether the same brain reward circuitry that is responsive to palatable rewards also encodes metabolic value independently of taste signaling. Here we show that trpm5−/− mice, which lack the cellular machinery required for sweet taste transduction, can develop a robust preference for sucrose solutions based solely on caloric content. Sucrose intake induced dopamine release in the ventral striatum of these sweet-blind mice, a pattern usually associated with receipt of palatable rewards. Furthermore, single neurons in this same ventral striatal region showed increased sensitivity to caloric intake even in the absence of gustatory inputs. Our findings suggest that calorie-rich nutrients can directly influence brain reward circuits that control food intake independently of palatability or functional taste transduction.
Full Article (Subscription only):
http://preview.tinyurl.com/57pgmn
Taipei 101 loaded with fireworks. 2007 - 2008
The Animator and the Seat
The Animator and the Seat
Try Not To Laugh
pretty much how I feel about it these days... (Blog Entry by smibbo)
Portal 2 is Coming! OHHH YESS!!!
CURB YOUR ENTHUSIASM * Girls Gone Wild
Animated video looks like 20´s ski posters. Legowelt
Deftones - Digital Bath
Greatest Play In Baseball - Rick Monday Saves U.S. Flag 1976
American Wedding - Gogol Bordello
New Slang - The Shins